Often, many people will have the ingredients to make homemade barbecue sauce on hand, which allows individuals to create their own if they happen to be out of the bottled bbq sauce of choice. With a complex taste, barbecue sauces are often as varied as the people who enjoy them. You can make barbecue sauce quickly through mixing ketchup and brown sugar, or you can make a more complex sauce for the occasions you want to stand out with your own creation.
Similar posts: stages of cancer
Similar posts: stages of cancer
- Mood:Cry
- Music:Mai Kuraki
Newsweek, 1971, “Ronald Reagan’s Slow Fade,” ended with the judgment that “the somber truth is that Sacramento may mark the end of Ronald Reagan’s political road. . . By every normal measure, Ronald Reagan ought to be entitled to any political future he wants. A close aide said, The Presidency? Oh, he’s not interested. Four more years and I think you’ll see Ronald Reagan riding one of his horses off into the sunset.” And see Stephen Roberts in the New York Times Magazine: “In 1976, the reasoning goes, Reagan would be 65, and too old to run.” “When a guy’s built on celluloid,” Democratic State Senator George Moscone said, “he goes up fast, but he burns out quickly.”
After the 1976 campaign, Newsweek offered a reprise, “Into the Sunset: The concluding line of Reagan’s convention speech—There is no substitute for victory—could also turn out to be a epitaph for his own political career.
And not to be left out, John Coyne wrote in some magazine called National Review that Reagan seems somewhat out of step with the new political stirrings, a man very much of the Sixties. . . For a decade he has been a central symbol of everything that is best in what we call the conservative movement, and if his approach and his ideas are obsolete, then so are those many of us who believe in him. And it’s never much fun to be a middle-aged anachronism.
Similar posts: stages of cancer
After the 1976 campaign, Newsweek offered a reprise, “Into the Sunset: The concluding line of Reagan’s convention speech—There is no substitute for victory—could also turn out to be a epitaph for his own political career.
And not to be left out, John Coyne wrote in some magazine called National Review that Reagan seems somewhat out of step with the new political stirrings, a man very much of the Sixties. . . For a decade he has been a central symbol of everything that is best in what we call the conservative movement, and if his approach and his ideas are obsolete, then so are those many of us who believe in him. And it’s never much fun to be a middle-aged anachronism.
Similar posts: stages of cancer
- Mood:Very good
- Music:Sukiyaki
Brain Injury
Over the course of a lifetime, the costs of a traumatic brain injury (TBI) can be tremendous. Depending of the severity of the injury, a person who has suffered a traumatic brain injury may be permanently unable to care for him or herself. Even in more moderate injury cases, a person who has suffered any brain damage may have difficulty remembering basic things and suffer from dizzy spells.
If you or someone you love has suffered a traumatic brain injury due to someone else's negligence, come to the law firm of Lederer Nojima LLP in Los Angeles, California. Contact us today to schedule your free initial consultation.
Working with a Team of Experts to Protect You
When you come to our firm, we'll prepare your legal claims to address the difficulties you will face for the rest of your life. In traumatic brain injury cases we routinely work with experts, including life care planners, who can help to fully assess the lifetime costs of such a serious injury. We also rely upon many of the top professionals in Southern California to provide expert medical testimony for our personal injury cases.
Traumatic brain injuries can arise in a wide range of circumstances. A car accident might result in permanent brain damage. A construction accident may result in permanent brain injuries and spine injuries. The mechanics of the various injuries may differ but the effect is identialc: i.e. the loss of function and capacity due to brain damage.
Personal Attention and Convenient Representation for Personal Injury Claims
We provide personal attention for all of our personal injury cases. When you come to the law firm of Lederer Nojima LLP, you will always deal directly with a personal injury attorney - not a paralegal or legal secretary. We will provide you with updates regarding your case throughout our legal representation of your claims.
We understand that it is often difficult for seriously injured people to travel. If you are homebound or in the hospital, we can come to visit you. We handle all of our personal injury cases on a contingency fee basis - you will pay no attorneys fees until we recover compensation for you.
Contact us today to schedule your free consultation. We often successfully represent people who have been turned down by other attorneys. Call us at 310-694-5907 to discuss your case.
Similar posts: stages of cancer
- Mood:More emotions
- Music:Southern All Stars
We've all experienced grief. We've all felt those intense rolling waves of emotion. But, do we all experience the same feelings each time we lose a loved one?
What Are The Stages of Grief?
Many people have tried to explain what grief is; some have even identified certain stages of grief.
Probably the most well-known of these might be from Elizabeth Kubler-Ross' book, "On Death and Dying." In it, she identified five stages that a dying patient experiences when informed of their terminal prognosis.
The stages Kubler-Ross identified are:
Denial (this isn't happening to me!)
Anger (why is this happening to me?)
Bargaining (I promise I'll be a better person if...)
Depression (I don't care anymore)
Acceptance (I'm ready for whatever comes)
Many people believe that these stages of grief are also experienced by others when they have lost a loved one.
Personally, I think of these definitions as emotional behaviors rather than stages, per se. I believe we may certainly experience some of these behaviors. But, I believe just as strongly, that there is no script for grief; that we cannot expect to feel any of our emotions in a particular set pattern. I do agree that acceptance is probably the last emotion felt, and in some instances it may be the only one.
A lesser known definition of the stages of grief is described by Dr. Roberta Temes in the book, "Living With An Empty Chair - a guide through grief." Temes describes three particular types of behavior exhibited by those suffering from grief and loss. They are:
Numbness (mechanical functioning and social insulation)
Disorganization (intensely painful feelings of loss)
Reorganization (re-entry into a more 'normal' social life.)
I am better able to relate to this definition as it seems to more accurately reflect the types of behavior I have experienced and observed. Within these types of behavior might well be most of the feelings described in Kubler-Ross' writings as well.
Which List Is Right?
In my opinion, both of these lists, and many others that we've all seen, are all descriptive of some of the emotions and functions we go through when we lose a loved one.
I believe that grief, like so many other things in our complex lives, can't be reduced to a neat list with absolute definitions, timelines, strategies, goals, and completion dates. Would that it were so easy
Grief is as individual as those of us who feel it, and as varied as the circumstances of death which occur.
Will I Go Through Every Stage?
If a 98-year old grandfather died in his sleep I think there would be different stages of grief and loss experienced than if a two-year old child were run over by a car and killed.
If a person has had a long life, death is somewhat expected as the natural scheme of things. There will be emotions of grief and loss but they might be more for what we will miss.
If a young life is cut short unexpectedly, there may well be feelings of denial, anger, bargaining, depression, and in some cases acceptance.
Just as we have different emotional reactions to anything that happens in our lives, so too, will we experience grief and loss in different ways. I think the important thing to remember is that there is a wide range of emotions that may be experienced; to expect to feel some of them and to know that we cannot completely control the process.
When Will I Be Through Grieving?
Grieving used to be much more ritualistic than it is today. In generations past there were set periods of time when certain customs must be observed:
Widows wore all black clothing for one year and drab colors forever after.
Mourners could not attend social gatherings for months.
Laughter and gaiety were discouraged for weeks or months.
Today we are unfettered by these restrictions and might even be confused about when we should be done grieving.
Actually, we'll probably never be done.
We'll never forget the person we grieve for. Our feelings may be tempered more with good memories than sadness as time passes, but that isn't to say that waves of raw emotion won't overcome us way after we thing we should be done.
I think the trick here is to understand that the feelings will occur, try to keep them in perspective, try to understand why you feel a certain way, and if there are any unresolved issues that cause particular emotional pain, forgive yourself and others and if necessary talk with someone about it.
There is no completion date to grieving...let your emotions flow through the stages of grief.
Similar posts: stages of cancer
What Are The Stages of Grief?
Many people have tried to explain what grief is; some have even identified certain stages of grief.
Probably the most well-known of these might be from Elizabeth Kubler-Ross' book, "On Death and Dying." In it, she identified five stages that a dying patient experiences when informed of their terminal prognosis.
The stages Kubler-Ross identified are:
Denial (this isn't happening to me!)
Anger (why is this happening to me?)
Bargaining (I promise I'll be a better person if...)
Depression (I don't care anymore)
Acceptance (I'm ready for whatever comes)
Many people believe that these stages of grief are also experienced by others when they have lost a loved one.
Personally, I think of these definitions as emotional behaviors rather than stages, per se. I believe we may certainly experience some of these behaviors. But, I believe just as strongly, that there is no script for grief; that we cannot expect to feel any of our emotions in a particular set pattern. I do agree that acceptance is probably the last emotion felt, and in some instances it may be the only one.
A lesser known definition of the stages of grief is described by Dr. Roberta Temes in the book, "Living With An Empty Chair - a guide through grief." Temes describes three particular types of behavior exhibited by those suffering from grief and loss. They are:
Numbness (mechanical functioning and social insulation)
Disorganization (intensely painful feelings of loss)
Reorganization (re-entry into a more 'normal' social life.)
I am better able to relate to this definition as it seems to more accurately reflect the types of behavior I have experienced and observed. Within these types of behavior might well be most of the feelings described in Kubler-Ross' writings as well.
Which List Is Right?
In my opinion, both of these lists, and many others that we've all seen, are all descriptive of some of the emotions and functions we go through when we lose a loved one.
I believe that grief, like so many other things in our complex lives, can't be reduced to a neat list with absolute definitions, timelines, strategies, goals, and completion dates. Would that it were so easy
Grief is as individual as those of us who feel it, and as varied as the circumstances of death which occur.
Will I Go Through Every Stage?
If a 98-year old grandfather died in his sleep I think there would be different stages of grief and loss experienced than if a two-year old child were run over by a car and killed.
If a person has had a long life, death is somewhat expected as the natural scheme of things. There will be emotions of grief and loss but they might be more for what we will miss.
If a young life is cut short unexpectedly, there may well be feelings of denial, anger, bargaining, depression, and in some cases acceptance.
Just as we have different emotional reactions to anything that happens in our lives, so too, will we experience grief and loss in different ways. I think the important thing to remember is that there is a wide range of emotions that may be experienced; to expect to feel some of them and to know that we cannot completely control the process.
When Will I Be Through Grieving?
Grieving used to be much more ritualistic than it is today. In generations past there were set periods of time when certain customs must be observed:
Widows wore all black clothing for one year and drab colors forever after.
Mourners could not attend social gatherings for months.
Laughter and gaiety were discouraged for weeks or months.
Today we are unfettered by these restrictions and might even be confused about when we should be done grieving.
Actually, we'll probably never be done.
We'll never forget the person we grieve for. Our feelings may be tempered more with good memories than sadness as time passes, but that isn't to say that waves of raw emotion won't overcome us way after we thing we should be done.
I think the trick here is to understand that the feelings will occur, try to keep them in perspective, try to understand why you feel a certain way, and if there are any unresolved issues that cause particular emotional pain, forgive yourself and others and if necessary talk with someone about it.
There is no completion date to grieving...let your emotions flow through the stages of grief.
Similar posts: stages of cancer
- Mood:Very good
- Music:Ami Suzuki
Multiple reasons may induce a woman to have a breast augmentation. Some will be motivated by considerations of the overall symmetry of their bodies, others might feel that currently their breasts are too small or that they present a form or shape they do not like. Any of these may be a reason to start thinking about the procedure. Also a lack of confidence in themselves often plays an important role. Just like being unhappy with ones nose, not being happy with ones breasts can do much harm to a persons self image. In many cases those that recovered from breast cancer have breast augmentation, because during the treatment of their illness they had tissue removed. A woman may decide to undergo an augmentation for a great many different reasons. In general though, the results are highly positive and have a great benefit both for the psychological health and the physical appearance of the patient.
Similar posts: stages of cancer
Similar posts: stages of cancer
- Mood:Cry
- Music:Ami Suzuki
Family Studies
Familial clustering of disease is a useful but not conclusive indicator of an underlying genetic etiology. Morganti and colleagues were perhaps the first to document, more than 40 years ago, the tendency of prostate cancer to cluster in families. Importantly, in 1960, a study in the Utah Mormon population by Woolf suggested that the likelihood of dying from prostate cancer was increased for men with affected first-degree relatives. Two large studies are of particular interest in addressing the issue of familial clustering of prostate cancer. Cannon-Albright et al. published a genetic epidemiologic study on prostate cancer also in the Utah Mormon population. Notably, prostate cancer showed the fourth strongest degree of familial clustering after lip, skin melanoma, and ovarian cancer. Prostate cancer had a higher familiarity than colon and breast carcinoma, two solid tumors that are well recognized as having a genetic or familial component.
A case-control study of patients treated for prostate cancer at Johns Hopkins was carried out by Steinberg et al. to assess the extent of familial aggregation in prostate cancer. Cancer pedigrees were obtained on 691 men with prostate cancer and 640 spouse controls. The only consistent risk factor for prostate cancer found in this study was a positive family history. Men with a father or brother affected were twice as likely to develop prostate cancer as men with no relatives affected. In addition, there was a trend of increasing risk with increasing number of affected family members such that men with two or three first-degree relatives affected had a five- and 11-fold increased risk of developing prostate cancer. Cox proportional hazards analysis in the case relatives revealed that risk was particularly increased to relatives of younger probands (less than 55 years). Evidence for aggregation of prostate cancer in families has been provided by many additional studies using either retrospective or cohort study designs. Five major findings emerged from these studies:
1. There is an increased risk for developing prostate cancer among the first- and second-degree relatives of prostate cancer patients.
2. The risk for developing prostate cancer among the first- and second-degree relatives increases with an increase in the number of affected individuals in the families.
3. The risk for developing prostate cancer among the first- and second-degree relatives increases with a decrease in the age at diagnosis of index prostate cancer cases.
4. Family history as an important risk factor for prostate cancer appears to be independent of ethnicity or race.
5. Having an affected brother tends to increase risk to a greater extent than does having a father with prostate cancer.
This latter tendency—that is, the increased risk associated with having an affected brother as compared to an affected father—prompted several authors to suggest a recessive or X-linked mode of inheritance for prostate cancer (see below).
Segregation Analyses
Whereas these studies consistently indicate a significant role for familial clustering as a risk factor for prostate cancer, both genetic components and common environmental risk factors shared within a family can lead to a significant finding in family studies. An estimation of contributions made by genetics as compared to environmental contributions can be determined through twin studies (see below) and complex segregation analyses. By testing the fit of several explicit models of inheritance (e.g., a major Mendelian gene model, an environmental model, or polygene model, or all) to the distribution of a disease in families, complex segregation analysis can identify the specific model that best describes the transmission of the disease in families. Three complex segregation analyses of prostate cancer have been reported, and each is consistent with the hypothesis that there is an autosomal dominant susceptibility gene ( 21,22 and 23). However, gene frequencies estimated by these studies vary appreciably (from 0.003 to 0.010), as do estimated gene penetrances (63% to 89% lifetime risk), presumably reflecting the different populations studied [families of radical prostatectomy patients in the Carter and Schaid studies vs. a population-based study by Gronberg ].
Twin Studies
The goal of twin studies is to compare the similarities (concordance rate) of a trait or disease in monozygotic and dizygotic twins as a means to dissect the genetic and environmental components of a familial aggregation. Twin studies by Gronberg et al. and Page et al. have observed higher concordance rates of prostate cancer in monozygotic twins compared to those of dizygotic twins, implicating a genetic contribution for familial aggregation of prostate cancer. More recently, in a large study of more than 44,000 Scandinavian twin pairs, Lichtenstein et al. reported a statistically significant effect of heritable factors for prostate cancer. Somewhat surprisingly, these authors suggested that heritable factors accounted for a larger proportion of prostate cancer (42%) than either breast or colorectal cancer.
Familial versus Hereditary Prostate Cancer
Based on their results of case-control and segregation analyses, Carter et al. proposed an operational definition of HPC that emphasized the factors of age of onset of disease and the number of affected family members as critical defining characteristics of a hereditary form of the disease. This group proposed the following definition of HPC: three or more affected individuals within one nuclear family, affected individuals in three successive generations on either the probands paternal or maternal lineages, or clustering of two or more individuals affected less than 55 years. Does this exclude families with only two members, affected at an older age, from the possibility of having a genetic form of the disease? The answer is definitely not, as there can certainly be families segregating high penetrance susceptibility alleles that are limited in numbers of affected individuals simply by having a small family size and a small number of male members. In addition, weaker genetic effects (e.g., those attributed to more common, low penetrance genes) may be very important in such smaller clusters and, in fact, may be more readily detected in studies of a large number of smaller prostate cancer families (e.g., affected sibling pairs). However, an important point for consideration, in terms of susceptibility gene mapping, is that a substantial proportion of families with only two first-degree relatives affected are quite likely to occur by chance, owing to the very high disease prevalence of prostate cancer. Obviously, the likelihood of chance clustering decreases as the number of affected men in a nuclear family increases, and it is not surprising that most of the rare high-penetrance cancer susceptibility genes that have been identified to date through linkage studies have been identified in large extended pedigrees with many affected members.
Clinical and Pathologic Characterization of Hereditary Prostate Cancer
To determine whether any differences might distinguish HPC from its sporadic counterpart, a number of clinical features of prostate cancer were examined by Carter et al. in patients with or without a family history of prostate cancer . Clinical stage at presentation, preoperative prostate-specific antigen level, final pathologic stage, and prostate weight were examined in a series of approximately 650 patients divided among three categories: those having HPC (as defined earlier), those with no other family members affected (i.e., sporadic), or those in whom there were other family members affected but not to the extent found in families classified as hereditary. No unique clinical or pathologic characteristic distinguished HPC in this group of patients in this study.
This lack of difference between hereditary and sporadic prostate cancer extends to the incidence of multifocality found for each of these categories. Based on studies of individuals harboring other cancer susceptibility alleles, in which multiple cancer foci are often observed in target organs, one might predict that prostate cancer would tend to be more multifocal in patients with a hereditary form of the disease. In a study by Bastacky et al., this was not found to be the case, however. As has been previously observed, prostate cancer in general is multifocal, and no difference was observed between sporadic and hereditary cases in this respect. Keetch et al. examined the pathologic characteristics of prostate cancers from men undergoing radical prostatectomy for treatment of clinically localized disease as a function of family history. The only difference observed was that familial cancers tended to have a slightly lower Gleason score.
Several studies have examined the effect of family history on outcome of prostate cancer after treatment. Bova et al. found no differences in progression rates as measured by prostate-specific antigen elevation in a cohort of men classified as having HPC compared to men with sporadic disease. Similarly, in a Swedish population study, Gronberg et al. found no significant differences in either overall or prostate cancer-specific survival between familial and sporadic prostate cancer cases. The spectrum of tumor grades at diagnosis in familial cases did not differ from that in a population with prostate cancer unselected for family history. These results led the authors to conclude that no differences in treatment between men with or without a positive family history of prostate cancer are justified at this time. In contrast, Kupelian et al. did observe a significant tendency for men with a positive family history to progress more rapidly after either surgical or radiation treatment for clinically localized disease. Additionally, Rodriguez et al. made the observation that men with a family history of prostate cancer are more likely to die from their disease [rate ratio (RR), 1.60; 95% confidence interval, 1.31 to 1.97]. Obviously, additional studies are needed to address this important question, particularly as our ability to define the phenotype of HPC becomes more refined.
Similar posts: stages of cancer
Familial clustering of disease is a useful but not conclusive indicator of an underlying genetic etiology. Morganti and colleagues were perhaps the first to document, more than 40 years ago, the tendency of prostate cancer to cluster in families. Importantly, in 1960, a study in the Utah Mormon population by Woolf suggested that the likelihood of dying from prostate cancer was increased for men with affected first-degree relatives. Two large studies are of particular interest in addressing the issue of familial clustering of prostate cancer. Cannon-Albright et al. published a genetic epidemiologic study on prostate cancer also in the Utah Mormon population. Notably, prostate cancer showed the fourth strongest degree of familial clustering after lip, skin melanoma, and ovarian cancer. Prostate cancer had a higher familiarity than colon and breast carcinoma, two solid tumors that are well recognized as having a genetic or familial component.
A case-control study of patients treated for prostate cancer at Johns Hopkins was carried out by Steinberg et al. to assess the extent of familial aggregation in prostate cancer. Cancer pedigrees were obtained on 691 men with prostate cancer and 640 spouse controls. The only consistent risk factor for prostate cancer found in this study was a positive family history. Men with a father or brother affected were twice as likely to develop prostate cancer as men with no relatives affected. In addition, there was a trend of increasing risk with increasing number of affected family members such that men with two or three first-degree relatives affected had a five- and 11-fold increased risk of developing prostate cancer. Cox proportional hazards analysis in the case relatives revealed that risk was particularly increased to relatives of younger probands (less than 55 years). Evidence for aggregation of prostate cancer in families has been provided by many additional studies using either retrospective or cohort study designs. Five major findings emerged from these studies:
1. There is an increased risk for developing prostate cancer among the first- and second-degree relatives of prostate cancer patients.
2. The risk for developing prostate cancer among the first- and second-degree relatives increases with an increase in the number of affected individuals in the families.
3. The risk for developing prostate cancer among the first- and second-degree relatives increases with a decrease in the age at diagnosis of index prostate cancer cases.
4. Family history as an important risk factor for prostate cancer appears to be independent of ethnicity or race.
5. Having an affected brother tends to increase risk to a greater extent than does having a father with prostate cancer.
This latter tendency—that is, the increased risk associated with having an affected brother as compared to an affected father—prompted several authors to suggest a recessive or X-linked mode of inheritance for prostate cancer (see below).
Segregation Analyses
Whereas these studies consistently indicate a significant role for familial clustering as a risk factor for prostate cancer, both genetic components and common environmental risk factors shared within a family can lead to a significant finding in family studies. An estimation of contributions made by genetics as compared to environmental contributions can be determined through twin studies (see below) and complex segregation analyses. By testing the fit of several explicit models of inheritance (e.g., a major Mendelian gene model, an environmental model, or polygene model, or all) to the distribution of a disease in families, complex segregation analysis can identify the specific model that best describes the transmission of the disease in families. Three complex segregation analyses of prostate cancer have been reported, and each is consistent with the hypothesis that there is an autosomal dominant susceptibility gene ( 21,22 and 23). However, gene frequencies estimated by these studies vary appreciably (from 0.003 to 0.010), as do estimated gene penetrances (63% to 89% lifetime risk), presumably reflecting the different populations studied [families of radical prostatectomy patients in the Carter and Schaid studies vs. a population-based study by Gronberg ].
Twin Studies
The goal of twin studies is to compare the similarities (concordance rate) of a trait or disease in monozygotic and dizygotic twins as a means to dissect the genetic and environmental components of a familial aggregation. Twin studies by Gronberg et al. and Page et al. have observed higher concordance rates of prostate cancer in monozygotic twins compared to those of dizygotic twins, implicating a genetic contribution for familial aggregation of prostate cancer. More recently, in a large study of more than 44,000 Scandinavian twin pairs, Lichtenstein et al. reported a statistically significant effect of heritable factors for prostate cancer. Somewhat surprisingly, these authors suggested that heritable factors accounted for a larger proportion of prostate cancer (42%) than either breast or colorectal cancer.
Familial versus Hereditary Prostate Cancer
Based on their results of case-control and segregation analyses, Carter et al. proposed an operational definition of HPC that emphasized the factors of age of onset of disease and the number of affected family members as critical defining characteristics of a hereditary form of the disease. This group proposed the following definition of HPC: three or more affected individuals within one nuclear family, affected individuals in three successive generations on either the probands paternal or maternal lineages, or clustering of two or more individuals affected less than 55 years. Does this exclude families with only two members, affected at an older age, from the possibility of having a genetic form of the disease? The answer is definitely not, as there can certainly be families segregating high penetrance susceptibility alleles that are limited in numbers of affected individuals simply by having a small family size and a small number of male members. In addition, weaker genetic effects (e.g., those attributed to more common, low penetrance genes) may be very important in such smaller clusters and, in fact, may be more readily detected in studies of a large number of smaller prostate cancer families (e.g., affected sibling pairs). However, an important point for consideration, in terms of susceptibility gene mapping, is that a substantial proportion of families with only two first-degree relatives affected are quite likely to occur by chance, owing to the very high disease prevalence of prostate cancer. Obviously, the likelihood of chance clustering decreases as the number of affected men in a nuclear family increases, and it is not surprising that most of the rare high-penetrance cancer susceptibility genes that have been identified to date through linkage studies have been identified in large extended pedigrees with many affected members.
Clinical and Pathologic Characterization of Hereditary Prostate Cancer
To determine whether any differences might distinguish HPC from its sporadic counterpart, a number of clinical features of prostate cancer were examined by Carter et al. in patients with or without a family history of prostate cancer . Clinical stage at presentation, preoperative prostate-specific antigen level, final pathologic stage, and prostate weight were examined in a series of approximately 650 patients divided among three categories: those having HPC (as defined earlier), those with no other family members affected (i.e., sporadic), or those in whom there were other family members affected but not to the extent found in families classified as hereditary. No unique clinical or pathologic characteristic distinguished HPC in this group of patients in this study.
This lack of difference between hereditary and sporadic prostate cancer extends to the incidence of multifocality found for each of these categories. Based on studies of individuals harboring other cancer susceptibility alleles, in which multiple cancer foci are often observed in target organs, one might predict that prostate cancer would tend to be more multifocal in patients with a hereditary form of the disease. In a study by Bastacky et al., this was not found to be the case, however. As has been previously observed, prostate cancer in general is multifocal, and no difference was observed between sporadic and hereditary cases in this respect. Keetch et al. examined the pathologic characteristics of prostate cancers from men undergoing radical prostatectomy for treatment of clinically localized disease as a function of family history. The only difference observed was that familial cancers tended to have a slightly lower Gleason score.
Several studies have examined the effect of family history on outcome of prostate cancer after treatment. Bova et al. found no differences in progression rates as measured by prostate-specific antigen elevation in a cohort of men classified as having HPC compared to men with sporadic disease. Similarly, in a Swedish population study, Gronberg et al. found no significant differences in either overall or prostate cancer-specific survival between familial and sporadic prostate cancer cases. The spectrum of tumor grades at diagnosis in familial cases did not differ from that in a population with prostate cancer unselected for family history. These results led the authors to conclude that no differences in treatment between men with or without a positive family history of prostate cancer are justified at this time. In contrast, Kupelian et al. did observe a significant tendency for men with a positive family history to progress more rapidly after either surgical or radiation treatment for clinically localized disease. Additionally, Rodriguez et al. made the observation that men with a family history of prostate cancer are more likely to die from their disease [rate ratio (RR), 1.60; 95% confidence interval, 1.31 to 1.97]. Obviously, additional studies are needed to address this important question, particularly as our ability to define the phenotype of HPC becomes more refined.
Similar posts: stages of cancer
- Mood:More emotions
- Music:Kumi Koda
Argument 1: The Aggregate of Qualities Argument
1. If God exists, God must necessarily possess all of several remarkable qualities (including supreme goodness, omnipotence, immortality, omniscience, ultimate creator, purpose giver).
2. Every one of these qualities may not exist in any one entity and if any such quality does exist it exists in few entities or in some cases (e.g. omnipotence, ultimate creator) in at most one entity.
3. Therefore it is highly unlikely any entity would possess even one of these qualities.
4. There is an infinitesimal chance that any one entity (given the almost infinite number of entities in the Universe) might possess the combination of even some two of these qualities, let alone all of them.
5. In statistical analysis a merely hypothetical infinitesimal chance can in effect be treated as the no chance to which it approximates so very closely.
6. Therefore as there is statistically such an infinitesimal chance of any entity possessing, as God would have to do, all God’s essential qualities in combination it can be said for all practical and statistical purposes that God just does not exist.
Argument 2: The Man And God Comprehension Gulf Argument
1. Man is finite (in time, space and power etc).
2. God if he exists is infinite (in time, space and power etc).
3. Therefore mankind cannot possibly recognise God or even know that God exists.
Argument 3: The ‘God Has No Explanatory Value’ Argument
1. God if he exists must be the ultimate being and provide the answer to all our ultimate questions - otherwise he is not really God.
2. Yet even supposing as a hypothesis that God exists the questions that God was supposed to finally answer still remain (though in some cases God is substituted in the question for the Universe).
3. Therefore hypothesising God’s existence is only unnecessarily adding an extra stage to such problems and has no real explanatory value.
4. Therefore according to Logic (Occam’s Razor Law - ‘that entities are not to be multiplied beyond necessity’) we should not postulate God’s existence and there is no adequate reason to suppose that God exists.
5. Therefore we should suppose that God does not exist.
Argument 4: The ‘This Is Not The Best Possible World’ Argument
1. God if he exists must be omnipotent, supremely good and our ultimate creator.
2. Therefore an existent God (being supremely good and competent) would have created the best possible world (if he created anything).
3. As the world is inconsistent (between ages and people) it cannot all be the best possible world.
4. Therefore as the world is not the best possible world, God cannot exist.
Argument 5: The Universal Uncertainty Argument
1. An uncertain God is a contradiction in terms.
2. Everything in the Universe must be fundamentally uncertain about its own relationship to the Universe as a whole because there is no way of attaining such certainty.
3. Therefore even an entity with all God’s other qualities cannot have the final quality of certain knowledge concerning its own relationship to the Universe as a whole.
4. Therefore God cannot exist because even any potential God cannot know for sure that it is God.
Note: Stated as a logical paradox this argument is ‘God cannot exist because God cannot know for sure that it is God’.
Argument 6: The ‘Some Of God’s Defining Qualities Cannot Exist’ Argument
1. God must have certain characteristic qualities (such as providing purpose to life), otherwise he would not be God.
2. But it is impossible for any entity to possess some of these qualities (such as providing purpose to life since we can find no real purpose and therefore we in practice have no ultimate purpose to our lives) that are essential to God.
3. Therefore since some of God’s essential qualities (such as being the purpose provider to life) cannot possibly exist in any entity, God cannot exist.
Similar posts: stages of cancer
1. If God exists, God must necessarily possess all of several remarkable qualities (including supreme goodness, omnipotence, immortality, omniscience, ultimate creator, purpose giver).
2. Every one of these qualities may not exist in any one entity and if any such quality does exist it exists in few entities or in some cases (e.g. omnipotence, ultimate creator) in at most one entity.
3. Therefore it is highly unlikely any entity would possess even one of these qualities.
4. There is an infinitesimal chance that any one entity (given the almost infinite number of entities in the Universe) might possess the combination of even some two of these qualities, let alone all of them.
5. In statistical analysis a merely hypothetical infinitesimal chance can in effect be treated as the no chance to which it approximates so very closely.
6. Therefore as there is statistically such an infinitesimal chance of any entity possessing, as God would have to do, all God’s essential qualities in combination it can be said for all practical and statistical purposes that God just does not exist.
Argument 2: The Man And God Comprehension Gulf Argument
1. Man is finite (in time, space and power etc).
2. God if he exists is infinite (in time, space and power etc).
3. Therefore mankind cannot possibly recognise God or even know that God exists.
Argument 3: The ‘God Has No Explanatory Value’ Argument
1. God if he exists must be the ultimate being and provide the answer to all our ultimate questions - otherwise he is not really God.
2. Yet even supposing as a hypothesis that God exists the questions that God was supposed to finally answer still remain (though in some cases God is substituted in the question for the Universe).
3. Therefore hypothesising God’s existence is only unnecessarily adding an extra stage to such problems and has no real explanatory value.
4. Therefore according to Logic (Occam’s Razor Law - ‘that entities are not to be multiplied beyond necessity’) we should not postulate God’s existence and there is no adequate reason to suppose that God exists.
5. Therefore we should suppose that God does not exist.
Argument 4: The ‘This Is Not The Best Possible World’ Argument
1. God if he exists must be omnipotent, supremely good and our ultimate creator.
2. Therefore an existent God (being supremely good and competent) would have created the best possible world (if he created anything).
3. As the world is inconsistent (between ages and people) it cannot all be the best possible world.
4. Therefore as the world is not the best possible world, God cannot exist.
Argument 5: The Universal Uncertainty Argument
1. An uncertain God is a contradiction in terms.
2. Everything in the Universe must be fundamentally uncertain about its own relationship to the Universe as a whole because there is no way of attaining such certainty.
3. Therefore even an entity with all God’s other qualities cannot have the final quality of certain knowledge concerning its own relationship to the Universe as a whole.
4. Therefore God cannot exist because even any potential God cannot know for sure that it is God.
Note: Stated as a logical paradox this argument is ‘God cannot exist because God cannot know for sure that it is God’.
Argument 6: The ‘Some Of God’s Defining Qualities Cannot Exist’ Argument
1. God must have certain characteristic qualities (such as providing purpose to life), otherwise he would not be God.
2. But it is impossible for any entity to possess some of these qualities (such as providing purpose to life since we can find no real purpose and therefore we in practice have no ultimate purpose to our lives) that are essential to God.
3. Therefore since some of God’s essential qualities (such as being the purpose provider to life) cannot possibly exist in any entity, God cannot exist.
Similar posts: stages of cancer
- Mood:Cry
- Music:Utada Hikaru
Multiple pregnancy complications - complications during pregnancy - is a very technical subject and its not easy to tackle it in a general way. Thus, I have made this post, which although technically inclined, there is no other way to deal with it. Nevertheless, there are many points here that may be highly relevant to you, so do please take some time to read, thank you!
Multiple pregnancy poses particular problems for women, their infants, and for their caregivers. Women are likely to experience the common, unpleasant symptoms of pregnancy, such as heartburn, backache, hemorrhoids, difficulty walking, and tiredness to a greater degree than women with a single pregnancy. They are more likely to suffer from anemia, hypertension, pre-eclampsia, pre-term labor, and operative delivery.
Similar posts: stages of cancer
- Mood:Very good
- Music:Southern All Stars
The most common use for chemotherapy in mesothelioma patients, is as an option for those who are not surgical candidates, however, various cancer centers are now conducting trials using the neoadjuvant approach. Alimta (pemetrexed) is a drug approved by the Food and Drug Administration (FDA) for use with Cisplatin in the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are not candidates for curative surgery. Alimta is the first drug approval specific to mesothelioma.
The Alimta/Cisplatin chemotherapy regimen is the first Food and Drug Administration (FDA) approved treatment specifically for malignant pleural mesothelioma. This is currently considered the most effective first-line treatment for mesothelioma patients who are not surgical candidates. A multi-targeted antifolate drug, Alimta works by blocking the enzymes necessary for DNA copying and cell division. During the clinical trial process, Alimta/Cisplatin improved median survival for pleural mesothelioma patients by approximately three months over treatment with Cisplatin as a single agent. Eli Lillys information on treatment with Alimta.
As with any medical treatment, it is important to discuss the use of Alimta with your doctor. This conversation should include all pertinent information regarding effectiveness, administration and possible side effects of the drug combination. It is also important to begin vitamin supplementation of B12 by injection during the week prior to treatment (to be repeated every 9 weeks), and folic acid by mouth daily (to be continued until 21 days after the last cycle of Alimta). Additionally, you will be given an oral steroid medication to minimize the risk of skin rash or other possible side effects. Your doctor will have information on the correct dosages of each medication. Be sure to tell your doctor of any other medications you are taking (including non-prescription drugs) so he may be aware of any adverse interactions.
Alimta/Cisplatin is administered to patients on an outpatient basis every 21 days. This cycle of treatment involves a 10-minute IV infusion of Alimta followed by a 2 hour infusion of Cisplatin. How many cycles of treatment you receive will be dependent on your response rate to the drug (regression of the tumor or halt to progression of the disease) and the side effects you might experience.
Side effects of Alimta/Cisplatin are mild to moderate for most mesothelioma patients, i.e., nausea, vomiting and fatigue, and can usually be managed by your doctor. For some patients, however, side effects may be debilitating, and may require a decrease in dosage or removal from the program. All potential side effects should be mentioned to your doctor. Never assume any complaint is minor.
Similar posts: stages of cancer
The Alimta/Cisplatin chemotherapy regimen is the first Food and Drug Administration (FDA) approved treatment specifically for malignant pleural mesothelioma. This is currently considered the most effective first-line treatment for mesothelioma patients who are not surgical candidates. A multi-targeted antifolate drug, Alimta works by blocking the enzymes necessary for DNA copying and cell division. During the clinical trial process, Alimta/Cisplatin improved median survival for pleural mesothelioma patients by approximately three months over treatment with Cisplatin as a single agent. Eli Lillys information on treatment with Alimta.
As with any medical treatment, it is important to discuss the use of Alimta with your doctor. This conversation should include all pertinent information regarding effectiveness, administration and possible side effects of the drug combination. It is also important to begin vitamin supplementation of B12 by injection during the week prior to treatment (to be repeated every 9 weeks), and folic acid by mouth daily (to be continued until 21 days after the last cycle of Alimta). Additionally, you will be given an oral steroid medication to minimize the risk of skin rash or other possible side effects. Your doctor will have information on the correct dosages of each medication. Be sure to tell your doctor of any other medications you are taking (including non-prescription drugs) so he may be aware of any adverse interactions.
Alimta/Cisplatin is administered to patients on an outpatient basis every 21 days. This cycle of treatment involves a 10-minute IV infusion of Alimta followed by a 2 hour infusion of Cisplatin. How many cycles of treatment you receive will be dependent on your response rate to the drug (regression of the tumor or halt to progression of the disease) and the side effects you might experience.
Side effects of Alimta/Cisplatin are mild to moderate for most mesothelioma patients, i.e., nausea, vomiting and fatigue, and can usually be managed by your doctor. For some patients, however, side effects may be debilitating, and may require a decrease in dosage or removal from the program. All potential side effects should be mentioned to your doctor. Never assume any complaint is minor.
Similar posts: stages of cancer
- Mood:Good
- Music:Sukiyaki
Defined Tag: Prostate Health.
Prostate problems are experienced by most men over the age of 50. This doesn't mean that you shouldn't worry about experiencing such when the time comes. You could always prevent the development of prostate problems as early as possible, and gain for yourself a healthy, enjoyable life way past the half-century mark of your existence, without having to be bothered by urination difficulties, enlarged glands, infertility, impotency and even the danger of death.
How?
By taking steps to ensure the best prostate health possible, of course.
Now, this is easier said than done, and it will require a certain degree of devotion and diligence from you. It may even require that you abandon some notions which you may have already embraced and which may have been deeply entrenched into your system.
But they are necessary for proper prostate health. Remember the saying "an ounce of prevention is worth more than a pound of cure?" Such a quote has never been more applicable than it is for prostate problems prevention. You should never ever think that it's too early to start worrying about prostate complication. There's no such thing as "too early" whenever we're dealing with the prostate.
The first thing that you should do to endure good prostate health is to study your personal conditions. Try answering the following questions:
Does your family have a history of prostate problems? This can be hereditary in nature. Just because an immediate relative of yours has been diagnosed with a prostate complication doesn't mean that you'll fall victim to such a disease, however. But it does place upon you a greater risk factor compared to that which is attached to people differently situated.
How old are you? Read this well, please: age determines when prostate problem symptoms would appear, but age does not determine when actual prostate problems truly start. Case in point: you may start experiencing softer erections once you reach 50, but this doesn't mean that prostate problems are just starting then. Often, the symptoms manifest after 5 or more years from the time the problem develops. Make it a point that you should have a general medical check-up once you reach the age of 30.
Do you know your prostate specific antigen (PSA) level? Maintaining a healthy PSA level is vital for good prostate health. But you could only determine this if you'd consult your doctor.
Though not everyone would possess the known risk factors that would endanger the health of the prostate, no one is completely spared from developing any (or all) of the three main prostate diseases. To prevent this from happening, answer the questions above as honestly as you could, and strongly consider taking the appropriate steps that they call for.
Similar posts: stages of cancer
- Mood:Good
- Music:Chage and Aska
How To Spot The Early Hieroglyphics Of Testicular Cancer
Although rare, Testicular Cancer is malignant if unbefriended untreated. This is something seeing legitimate is reported that a lot of femininity are unconcerned by the exigency to check themselves ofttimes for segment thinkable warning symbols.
This article aims to look after some instruction cast the likely symptoms of testicular cancer. This contour of cancer is curable if sound is detected early. And so read this article and hold dear undoubted could save your life.
Able are three forms of testicular cancer that onus symbolize diagnosed. The Seminoma scheme is the cancer of a single cell moment the testicles, non - Seminomas are several cells. These forms of cancer ofttimes influence manhood between the ages of 15 to 45. Lymphoma cancer much affects older sex, typically over the age of 50 and is much rarer.
The figures recorded flaunt that the differing forms of testicular cancer are still unusual. Of all the cancers diagnosed each tempo, approximately 1 % of them are related to the testicles. Fix the United States 8, 000 new cases are recorded each second, of which around 95 % compose a full recovery. These figures showing that early detection rap significantly perk up the preference of a full recovery.
Ergo what symptoms are average fix the early forms of testicular cancer? Conceivably the most frequent symptom is the statement of a lump on one of the testicles or perhaps abnormal swelling that may end credit torture or discomfort. The malaise may hold office sharp and casual. Juice some cases the testicles may shrink.
You may proof a sensitivity of heaviness hold the scrotum or affliction leverage the lower back area or groin. Some sexuality obtain besides reported early symbols of testicular cancer prerogative the mold of persistent belly pains.
This onus create a tiredness or sense of enervate prerogative your general stretch to generation activities. Unaffected is again possible for some masculinity to report no symptoms or not awareness ill or pooped out abbot to diagnosis.
Occasionally, the onslaught of testicular cancer authority epitomize detected buttoned up a series of noteworthy symptoms. Some male keep reported a swelling prerogative the breast area or the tissue sway the senior torso has emerge as sore and trying. The nipples may further become actual sore.
If the initial symptoms retain been ignored or they did not display themselves early, for leverage some worse cases subsequent the cancer has spread irrefutable boundness speak for detected concluded other symptoms. Typically testicular cancer tends to spread to the resistant system and infrequently affects other areas of the body.
Conditions cognate due to strength of the chest, coughing and problems adumbrate aware are fixed of the cancer perfecting to the lungs and the lymph nodes.
Of course, sincere is large to point out that these symptoms are vague and could body something or possibly fly speck farther than stress - related symptoms. Nonetheless, firm is exceptional to impersonate sheltered and forasmuch as if you familiarity factor of the extensive symptoms whence you should consult your doctor whereas at once now possible.
Remind inertia or dismissal of the symptoms will not sire live disappear. Secure real that you share a moment each past you share a shower or bath to check your testicles for bit irregular lumps or swelling.
Selection to act sooner somewhat than later authority equate the particularity between survival and becoming one of the unsuccessful 400 sexuality who die of testicular cancer every clock dominion the United States.
Similar posts: stages of cancer
- Mood:Cry
- Music:Heartbreak Hotel
Turns out, the event is the Volvo Ocean Race -- a 9 month yacht race around the world. An article quotes chief mktg. officer Anthony (Tony) Bertone saying, "A lot of time people see sailing as an elite sport, but we're trying to give folks an opportunity to see that's not the case." But I'm going to have to disagree w/ him -- I find sailing to be very much an elite sport. Ok, I'll admit: I went to prep school, and I even spent a season with the Milton Academy sailing team (I was a bench-warmer; I swear, the only reason I joined was b/c the managers on my ice hockey team were the captains for the sailing team! They encouraged me to join. It was...an experience. I no longer sail.)
Anyway, the project makes a lot of sense in terms of Boston sports, as sailing is somewhat popular here (or at least there are a lot of universities in Boston that have sailing teams). However, DJ battles? Mixing a rich white kids' sport with hip-hop culture? I'm not saying it can't be done, but bringing sailing to the streets seems like a far-reach to me. (Ok, so I can see Topsiders becoming a hipster fad.) I guess with a large enough marketing budget, perhaps dichotomous cultures can mingle, even if it's only for 3 weeks. But hey, I'll have to go see it for myself.
Similar posts: stages of cancer
Anyway, the project makes a lot of sense in terms of Boston sports, as sailing is somewhat popular here (or at least there are a lot of universities in Boston that have sailing teams). However, DJ battles? Mixing a rich white kids' sport with hip-hop culture? I'm not saying it can't be done, but bringing sailing to the streets seems like a far-reach to me. (Ok, so I can see Topsiders becoming a hipster fad.) I guess with a large enough marketing budget, perhaps dichotomous cultures can mingle, even if it's only for 3 weeks. But hey, I'll have to go see it for myself.
Similar posts: stages of cancer
- Mood:Cry
- Music:Ami Suzuki
Dildos are for penetration, pure and simple. They don't vibrate, move, dance or sing, they just fit well in the hand and in whatever orifice you choose to use. Imagine it: your perfect penis.
With a dildo, you can pick the style, size, shape, length, width, texture and color that appeals to your particular sense of whimsy. You can select a long, short, nubby, smooth, realistic, modern, black, white or purple dildo, a dildo with testicles attached, one with suction cups that allow the dildo to adhere to the surface of your choice, or a futuristic dildo with assorted bells, whistles and gewgaws.
Vibrators vibrate; dildos fill space, whether it be vaginal or anal. While lots of people enjoy the stimuli vibrators produce, many others enjoy the feeling of fullness a dildo provides, as well as the level of thrusting control they can experience with this stationary device.
Traditional Dildos
A traditional dildo is shaped like a phallus, which means it vaguely resembles a penis. Some can be quite realistic, especially if they're made from silicone. Others look nothing like the male member. They come in all sizes, shapes, textures and colors, from the smallest insertable to the (laughably) huge twelve-inch dildo. However, they all have one thing in common: they were made for thrusting.
When considering a traditional dildo, think about what you want. Some people prefer the simple sleekness of a smooth jelly dong. Others enjoy a more realistic shape and texture. Some people like small traditional dildos and others like obscenely large ones. It's really up to you. You might try experimenting with different vegetables to determine what size works best for you. When you find a veggie that fits just right, hunt for a traditional dildo of approximate size and shape. If you're not comfortable with the vegetarian approach, you may have to let trial and error determine your acceptable girth. As for texture, stroke a few floor models if you're shopping live. Pick the material that appeals to you most. If you don't find it potentially erotic, it's a colossal waste of time.
Traditional dildos are available in a variety of different styles, most of which can be categorized into the following groups:
Realistic dildo look just like the real thing -- in fact, they're often cast from molds created from real penises. Like all sex toys, realistic dildos come in a variety of sizes, shapes, textures and skin tones, ranging from a healthy six inches to a whopping foot and a half. Most realistic dildos are made from silicone, jelly or rubber-- textures that closely resemble human skin. Many realistic dildos have testicles, veins and other natural anomalies. Increasingly popular are those cast from famous penises -- those belonging to popular adult film stars! Some people really enjoy the heft and natural look of these toys; others are a bit intimidated by these members.
Smooth Dildos: Similar to slimline vibrators, these dildos are smooth, sleek and seamless, usually constructed of silicone, jelly or translucent rubber. These toys are relatively uncommon; the lack of friction makes them undesirable for many people. However, like all sex toys, they have their devotees: some people swear the smooth ride is delectable.
G-Spot dildos come in two basic shapes: long, smooth shafts with a tilted tip, and stubby, knobby thick shafts with wide midsections. Whichever your preference, both function in relatively the same way -- they're designed to hit a woman's G-Spot, that elusive area about three inches into the vaginal canal. Women point the knobby or tilted end upward, toward the magical spot, and apply pressure. This type of dildo isn't particularly appealing to women who don't enjoy G-Spot stimulation, but those who do say G-Spot dildos are incredible. If you aren't sure about your tastes, try one out. You might really like it. If you're interested in finding out if G-Spot stimulation is for you, these dildos are a good way to begin play. Use lots of lube and remember that most women respond to firm G-Spot pressure, not gentle stroking. These types of dildos are also great for stimulating the prostate.
"Other" Dildos For whatever reason, some people prefer that their sex toys resemble anything but a penis. We've seen silicone, jelly and rubber vegetables, dolphins, mysterious wand-like creations, space-age designs with little dangly things hanging off the end -- we don't question anything! If a particular dildo exists, as weird as it may look, it must have a market. Keep an open mind and give it a try.
Some women prefer traditional dildos because using them seems more like traditional intercourse, but offer more control. In fact, some men have been known to become jealous of their partner's buddy -- why would any woman with an always-erect penis at her disposal want a big, messy man around the house? Never fear, guys. A traditional dildo can provide crashing orgasms, but it can't provide the intimacy and touch that you can..
Anal Dildos
Although some people aren't comfortable with the idea of anal play or penetration, an increasingly large number of people enjoy the intense stimulation afforded by the sensitive nerve endings found in the anus. Whether you enjoy light or deep penetration, slim or thick girth, smooth entry or lots of friction, remember to select a smooth, seamless toy for anal play, one with a flared or larger base. You don't want your toy to get lost in your rectum!
Three additional things are critical for safe anal play: communication, relaxation, and lots and lots of lubrication. Unlike a woman's vagina, the anal canal doesn't produce any sort of lubrication. The last thing you want to experience during anal play is the sharp, shooting pains that can accompany the insertion of a dry dildo. Take it slow, be gentle, and respect your partner's boundaries.
While many kinds of dildos can be used for anal play, you should always select one with a flared base so it doesn't slip in farther than you intend. The last thing you want to become is an emergency-room anecdote! For safest play, select a dildo that has been specifically designed for anal play.
Available in all sizes and shapes, anal dildos have a wide, flared base attached to a tapering shaft, which can vary in size and shape from a long, twisted phallus-shaped rod, to a short, stocky model that can be worn without restraint. Many people enjoy the sensation of fullness, similar to the sensation women experience during vaginal penetration. Other people employ a thrusting motion with their anal dildos. Whatever works. Just be gentle -- otherwise you risk anal fissures and a host of other complications.
Double-Ended Dildos
These party toys are meant for two; a double dildo is nothing more than two realistic dildos joined at the base -- with a little extra wiggle room. Any hetero- or homosexual combination can make good use of a double dildo (or "double dong," as they're sometimes called): man and man, man and woman, and woman and woman. Usually not a great choice for newbies (these dildos can appear alarmingly large), double dildos can make a tasteful addition to the true connoisseur's treasure chest.
Beads Balls
Non-vibrating beads and balls provide gentle, erotic stimulation vaginally or anally. Joined balls, often classified as "anal balls" (although you can use them vaginally, also), are inserted then slowly withdrawn for a delicious sensation. Loose balls, often called "Ben Wa Balls," are inserted into the vagina and then rolled around internally for a subtle sensation.
Some people really enjoy the subtle sensations produced by these types of toys. Others say that beads and balls don't do much for them. Either way, you'll experience a totally different sensation than you would with a vibrator or regular dildo, so be patient and keep an open mind. You might find a new favorite.
Similar posts: stages of cancer
With a dildo, you can pick the style, size, shape, length, width, texture and color that appeals to your particular sense of whimsy. You can select a long, short, nubby, smooth, realistic, modern, black, white or purple dildo, a dildo with testicles attached, one with suction cups that allow the dildo to adhere to the surface of your choice, or a futuristic dildo with assorted bells, whistles and gewgaws.
Vibrators vibrate; dildos fill space, whether it be vaginal or anal. While lots of people enjoy the stimuli vibrators produce, many others enjoy the feeling of fullness a dildo provides, as well as the level of thrusting control they can experience with this stationary device.
Traditional Dildos
A traditional dildo is shaped like a phallus, which means it vaguely resembles a penis. Some can be quite realistic, especially if they're made from silicone. Others look nothing like the male member. They come in all sizes, shapes, textures and colors, from the smallest insertable to the (laughably) huge twelve-inch dildo. However, they all have one thing in common: they were made for thrusting.
When considering a traditional dildo, think about what you want. Some people prefer the simple sleekness of a smooth jelly dong. Others enjoy a more realistic shape and texture. Some people like small traditional dildos and others like obscenely large ones. It's really up to you. You might try experimenting with different vegetables to determine what size works best for you. When you find a veggie that fits just right, hunt for a traditional dildo of approximate size and shape. If you're not comfortable with the vegetarian approach, you may have to let trial and error determine your acceptable girth. As for texture, stroke a few floor models if you're shopping live. Pick the material that appeals to you most. If you don't find it potentially erotic, it's a colossal waste of time.
Traditional dildos are available in a variety of different styles, most of which can be categorized into the following groups:
Realistic dildo look just like the real thing -- in fact, they're often cast from molds created from real penises. Like all sex toys, realistic dildos come in a variety of sizes, shapes, textures and skin tones, ranging from a healthy six inches to a whopping foot and a half. Most realistic dildos are made from silicone, jelly or rubber-- textures that closely resemble human skin. Many realistic dildos have testicles, veins and other natural anomalies. Increasingly popular are those cast from famous penises -- those belonging to popular adult film stars! Some people really enjoy the heft and natural look of these toys; others are a bit intimidated by these members.
Smooth Dildos: Similar to slimline vibrators, these dildos are smooth, sleek and seamless, usually constructed of silicone, jelly or translucent rubber. These toys are relatively uncommon; the lack of friction makes them undesirable for many people. However, like all sex toys, they have their devotees: some people swear the smooth ride is delectable.
G-Spot dildos come in two basic shapes: long, smooth shafts with a tilted tip, and stubby, knobby thick shafts with wide midsections. Whichever your preference, both function in relatively the same way -- they're designed to hit a woman's G-Spot, that elusive area about three inches into the vaginal canal. Women point the knobby or tilted end upward, toward the magical spot, and apply pressure. This type of dildo isn't particularly appealing to women who don't enjoy G-Spot stimulation, but those who do say G-Spot dildos are incredible. If you aren't sure about your tastes, try one out. You might really like it. If you're interested in finding out if G-Spot stimulation is for you, these dildos are a good way to begin play. Use lots of lube and remember that most women respond to firm G-Spot pressure, not gentle stroking. These types of dildos are also great for stimulating the prostate.
"Other" Dildos For whatever reason, some people prefer that their sex toys resemble anything but a penis. We've seen silicone, jelly and rubber vegetables, dolphins, mysterious wand-like creations, space-age designs with little dangly things hanging off the end -- we don't question anything! If a particular dildo exists, as weird as it may look, it must have a market. Keep an open mind and give it a try.
Some women prefer traditional dildos because using them seems more like traditional intercourse, but offer more control. In fact, some men have been known to become jealous of their partner's buddy -- why would any woman with an always-erect penis at her disposal want a big, messy man around the house? Never fear, guys. A traditional dildo can provide crashing orgasms, but it can't provide the intimacy and touch that you can..
Anal Dildos
Although some people aren't comfortable with the idea of anal play or penetration, an increasingly large number of people enjoy the intense stimulation afforded by the sensitive nerve endings found in the anus. Whether you enjoy light or deep penetration, slim or thick girth, smooth entry or lots of friction, remember to select a smooth, seamless toy for anal play, one with a flared or larger base. You don't want your toy to get lost in your rectum!
Three additional things are critical for safe anal play: communication, relaxation, and lots and lots of lubrication. Unlike a woman's vagina, the anal canal doesn't produce any sort of lubrication. The last thing you want to experience during anal play is the sharp, shooting pains that can accompany the insertion of a dry dildo. Take it slow, be gentle, and respect your partner's boundaries.
While many kinds of dildos can be used for anal play, you should always select one with a flared base so it doesn't slip in farther than you intend. The last thing you want to become is an emergency-room anecdote! For safest play, select a dildo that has been specifically designed for anal play.
Available in all sizes and shapes, anal dildos have a wide, flared base attached to a tapering shaft, which can vary in size and shape from a long, twisted phallus-shaped rod, to a short, stocky model that can be worn without restraint. Many people enjoy the sensation of fullness, similar to the sensation women experience during vaginal penetration. Other people employ a thrusting motion with their anal dildos. Whatever works. Just be gentle -- otherwise you risk anal fissures and a host of other complications.
Double-Ended Dildos
These party toys are meant for two; a double dildo is nothing more than two realistic dildos joined at the base -- with a little extra wiggle room. Any hetero- or homosexual combination can make good use of a double dildo (or "double dong," as they're sometimes called): man and man, man and woman, and woman and woman. Usually not a great choice for newbies (these dildos can appear alarmingly large), double dildos can make a tasteful addition to the true connoisseur's treasure chest.
Beads Balls
Non-vibrating beads and balls provide gentle, erotic stimulation vaginally or anally. Joined balls, often classified as "anal balls" (although you can use them vaginally, also), are inserted then slowly withdrawn for a delicious sensation. Loose balls, often called "Ben Wa Balls," are inserted into the vagina and then rolled around internally for a subtle sensation.
Some people really enjoy the subtle sensations produced by these types of toys. Others say that beads and balls don't do much for them. Either way, you'll experience a totally different sensation than you would with a vibrator or regular dildo, so be patient and keep an open mind. You might find a new favorite.
Similar posts: stages of cancer
- Mood:Very good
- Music:Namie Amuro
Most people diagnosed with this form of mesothelioma are not good candidates for cancer surgery. However, there are rare cases where the cancer is diagnosed early, and surgery can be carried out to remove small, localized pericardial tumors. This type of surgery carries great risk, simply due to the proximity of the heart.
Prognosis for those with pericardial mesothelioma is grim and palliative treatment is usually the only option for people diagnosed with pericardial mesothelioma. This type of treatment is performed to improve a patient's quality of life, and reduce the severity of symptoms caused by the build-up of fluid in the pericardium. Fine needle aspiration may be carried out to remove excess fluid as well. In some cases, radiation therapy may be an option. Unfortunately, the proximity of the heart and lungs make this a risky prospect.
Similar posts: stages of cancer
Prognosis for those with pericardial mesothelioma is grim and palliative treatment is usually the only option for people diagnosed with pericardial mesothelioma. This type of treatment is performed to improve a patient's quality of life, and reduce the severity of symptoms caused by the build-up of fluid in the pericardium. Fine needle aspiration may be carried out to remove excess fluid as well. In some cases, radiation therapy may be an option. Unfortunately, the proximity of the heart and lungs make this a risky prospect.
Similar posts: stages of cancer
- Mood:Very good
- Music:Mai Kuraki
Natural cures for Cancer? Is that possible? In a world where the Pharmaceutical giants would have people believe that the only way to deal with any illness is via their fancy and expensive drugs it is comforting to know that there are alternatives. Natural cures and remedies are available to treat almost any illness and Cancer is not an exception.
Cancer touches the lives of so many people with such profound effect. Fear and confusion, pain and anguish all have their say, and the often harsh treatments prescribed bring with them additional physical and emotional stresses. Natural cures for Cancer can offer alternative approaches to treatment which help the body to heal itself and in doing so give relief in a much more comfortable and sympathetic way.
Chemotherapy, in its fight to eradicate Cancerous cells from the body, can have some pretty alarming side effects. Loss of hair is the obvious visual effect that most of us are familiar with but the list of other possible complications from the use of Chemotherapy Thirteen drugs is extensive. Prolonged vomiting, tissue death (Necrosis), lethargy, damage to bone marrow, muscle movement co-ordination difficulty (Ataxis), Cellulite, hardening of veins (Phlebosclerosis), Liver and/or Kidney failure, these are only a selection of the side effects often experienced. Surgery and Radiation Treatment also have their own risks.
At a time when the body is already using precious energy to combat the effects of a cancerous invasion just one, let alone a combination, of these unwanted side effects could be enough to hasten the spread of the disease. In studies conducted by leading US doctors, The Harvard School of Public Health, and noted by the American Medical Association, results have indicated that patients who refused medical procedures enjoyed a lesser rate of mortality than those who had accepted. As an example, one such study suggests that patients suffering Breast Cancer had a life expectancy four times longer without conventional treatment than would be the case if a conventional treatment regimen were followed. Yet doctors continue to prescribe these treatments. Why?
Most would suspect one simple reason, MONEY. It has been estimated that one single average cancer patient in the US can generate in excess of $1 million in revenues to the cancer industry. It becomes easy to understand why doctors will not explore the use of Natural Cures for Cancer when surgical and pharmaceutical treatments carry such high $ values.
Natural Cancer Cures are gentle and non invasive. Where Chemo attacks the body in its efforts to destroy cancer cells, natural remedies work with the bodys natural defences to heal without the risk of side effects, and without the risk of the treatment actually being more dangerous than the cancer itself.
Natural Cancer Cures are real and should not be dismissed without serious consideration.
Similar posts: stages of cancer
Cancer touches the lives of so many people with such profound effect. Fear and confusion, pain and anguish all have their say, and the often harsh treatments prescribed bring with them additional physical and emotional stresses. Natural cures for Cancer can offer alternative approaches to treatment which help the body to heal itself and in doing so give relief in a much more comfortable and sympathetic way.
Chemotherapy, in its fight to eradicate Cancerous cells from the body, can have some pretty alarming side effects. Loss of hair is the obvious visual effect that most of us are familiar with but the list of other possible complications from the use of Chemotherapy Thirteen drugs is extensive. Prolonged vomiting, tissue death (Necrosis), lethargy, damage to bone marrow, muscle movement co-ordination difficulty (Ataxis), Cellulite, hardening of veins (Phlebosclerosis), Liver and/or Kidney failure, these are only a selection of the side effects often experienced. Surgery and Radiation Treatment also have their own risks.
At a time when the body is already using precious energy to combat the effects of a cancerous invasion just one, let alone a combination, of these unwanted side effects could be enough to hasten the spread of the disease. In studies conducted by leading US doctors, The Harvard School of Public Health, and noted by the American Medical Association, results have indicated that patients who refused medical procedures enjoyed a lesser rate of mortality than those who had accepted. As an example, one such study suggests that patients suffering Breast Cancer had a life expectancy four times longer without conventional treatment than would be the case if a conventional treatment regimen were followed. Yet doctors continue to prescribe these treatments. Why?
Most would suspect one simple reason, MONEY. It has been estimated that one single average cancer patient in the US can generate in excess of $1 million in revenues to the cancer industry. It becomes easy to understand why doctors will not explore the use of Natural Cures for Cancer when surgical and pharmaceutical treatments carry such high $ values.
Natural Cancer Cures are gentle and non invasive. Where Chemo attacks the body in its efforts to destroy cancer cells, natural remedies work with the bodys natural defences to heal without the risk of side effects, and without the risk of the treatment actually being more dangerous than the cancer itself.
Natural Cancer Cures are real and should not be dismissed without serious consideration.
Similar posts: stages of cancer
- Mood:Cry
- Music:Namie Amuro
A first-time designer with the nickname PONR in this WGM posted the Robot Zebra Nike Dunks at the Nike Talk thread linked here. While the Robot Zebra Nike Dunks may need a bit of cleanup, PONR in this WGM did a solid job for his first time. We can see where these custom Dunks are heading even if the finer touches have not been sharpened.
The designer painted the middle panel, Nike swoosh and heel tag black as a solid base for the robot zebra print. He painted the remainder of these custom sneakers silver with black stripes to create a futuristic take on the familiar zebra print. The tongue was kept its original white color which may be changed as PONR in this WGM revises the look of the Robot Zebra Dunks.
A closer inspection of these custom Dunks show a few spots where the black and silver paint did not quite cover up the original paint job. The designer has recognized these problems and I hope that he builds from this experience by creating more sneakers in the future. I like the artistic view that PONR in this WGM took with these Dunks, a vision that will become more refined with practice.
Similar posts: stages of cancer
- Mood:Good
- Music:Kumi Koda
A study conducted by the Graduate Hospital in Philadelphia found that sleeping on you left side is the best way to avoid nighttime heartburn. Sleeping on your right side may increase your heartburn symptoms because the acid takes longer to clear out of your esophagus when you lay on your right side. While sleeping on your back can allow acid to slip back into your esophagus more often, sleeping with your head elevated, such as on a wedge pillow, will allow gravity to keep the acid in your stomach. There are other tips you can follow to help prevent nighttime heartburn.
Similar posts: stages of cancer
Similar posts: stages of cancer
- Mood:Good
- Music:Mai Kuraki
Cancer is not one disease. It is an overgrowth of an organ or a part of your body. If you have an overgrowth in your brain, it can have problems and complications entirely different from an overgrowth of your thyroid gland.
Can soneone explain this better ? What do thay mean by types of cancer or not all cancer is the same?
Than why are some cancer there is a cure.
Similar posts: stages of cancer
Can soneone explain this better ? What do thay mean by types of cancer or not all cancer is the same?
Than why are some cancer there is a cure.
Similar posts: stages of cancer
- Mood:More emotions
- Music:Ami Suzuki
Although dentistry provides our patients with a multitude of services from tooth repair and periodontal (gum) therapies to pain management and aesthetic reconstruction, we must not over look the importance of a potential life saving practice that consists of an oral cancer screening.
The following information should reinforce the importance of an oral cancer screening.
Statistics: In 2008, in the U.S. alone, about 34,000 individuals will be diagnosed with oral cancer. 66% of the time these will be found as late stage III or IV disease. Low public awareness of the disease is a significant factor, but these cancers could be found at early, highly survivable stages through a simple, painless 1 minute examination by a trained dental professional or other health care provider.
Risk Factors: Research has identified a number of factors that may contribute to the development of oral cancer. The most common are the use of tobacco and alcohol. Others include poor hygiene, irritation caused by ill-fitting dentures and rough surfaces on teeth, poor nutrition, some chronic infections and combinations of these factors.
Signs and Symptoms: Unfortunately, in its early stages, oral cancer can go unnoticed. It may first look like a common ulcer, cold sore or a discoloration of tissue. Usually it involves the tissue of the lips or the tongue, floor of the mouth, cheek lining, gums, or the palate (roof of the mouth).
Fortunately, your dentist can see or feel if a lesion looks cancerous. If you have any type of lesion in your mouth, or on your lips, that doesnt heal within two weeks, or a difficulty in swallowing for a prolonged period of time, it is very important to see your dentist right away.
If your dentist does find a suspicious lesion in your mouth, he/she might remove it, but will most likely send you to a specialist for removal and biopsy, which is a painless procedure.
Treatment: Surgical excision (removal) of the tumor is usually recommended if the tumor is small enough. Conventional therapies also provide radiation and chemotherapy. However, there are more and more alternative, holistic treatments designed to stimulate and strengthen the immune system that are being used today with surprisingly positive results. A combination of these two modalities might provide the body with its best chance for a successful outcome.
Prevention: The best preventions of oral cancer is not to use tobacco and only drink alcohol in moderation. Avoid prolonged exposure to sun or use a sunscreen on your lips. Also, dont forget to visit your dentist every 6 months for regular check-ups.
Our standard policy includes an oral cancer screening for every new patient dental evaluation as well as all regular check-ups and teeth cleanings. The screening only takes about 60 seconds and consists of a simple visual examination for any presence of cancer.
If youre not currently receiving this exam, please insist that your dentist add this to his protocol. It cannot and should not be ignored. You deserve this special care and it may even save your life.
Dr. Michael Rehme, DDS, CCN, practices Biological Dentistry that includes mercury free, tooth colored fillings; healthy dental materials; balancing body chemistry; and nutritional therapy. For more information about Biological Dentistry and Patient Success Stories visit http://www.ToothAndBodyConnection.com
Attend a free monthly presentation by Dr. Rehme on Biological Dentistry in the seminar room of his newly expanded office on the third Tuesday of each month @ 6:30pm. Please call to verify and reserve your space 314-997-2550.
Similar posts: stages of cancer
The following information should reinforce the importance of an oral cancer screening.
Statistics: In 2008, in the U.S. alone, about 34,000 individuals will be diagnosed with oral cancer. 66% of the time these will be found as late stage III or IV disease. Low public awareness of the disease is a significant factor, but these cancers could be found at early, highly survivable stages through a simple, painless 1 minute examination by a trained dental professional or other health care provider.
Risk Factors: Research has identified a number of factors that may contribute to the development of oral cancer. The most common are the use of tobacco and alcohol. Others include poor hygiene, irritation caused by ill-fitting dentures and rough surfaces on teeth, poor nutrition, some chronic infections and combinations of these factors.
Signs and Symptoms: Unfortunately, in its early stages, oral cancer can go unnoticed. It may first look like a common ulcer, cold sore or a discoloration of tissue. Usually it involves the tissue of the lips or the tongue, floor of the mouth, cheek lining, gums, or the palate (roof of the mouth).
Fortunately, your dentist can see or feel if a lesion looks cancerous. If you have any type of lesion in your mouth, or on your lips, that doesnt heal within two weeks, or a difficulty in swallowing for a prolonged period of time, it is very important to see your dentist right away.
If your dentist does find a suspicious lesion in your mouth, he/she might remove it, but will most likely send you to a specialist for removal and biopsy, which is a painless procedure.
Treatment: Surgical excision (removal) of the tumor is usually recommended if the tumor is small enough. Conventional therapies also provide radiation and chemotherapy. However, there are more and more alternative, holistic treatments designed to stimulate and strengthen the immune system that are being used today with surprisingly positive results. A combination of these two modalities might provide the body with its best chance for a successful outcome.
Prevention: The best preventions of oral cancer is not to use tobacco and only drink alcohol in moderation. Avoid prolonged exposure to sun or use a sunscreen on your lips. Also, dont forget to visit your dentist every 6 months for regular check-ups.
Our standard policy includes an oral cancer screening for every new patient dental evaluation as well as all regular check-ups and teeth cleanings. The screening only takes about 60 seconds and consists of a simple visual examination for any presence of cancer.
If youre not currently receiving this exam, please insist that your dentist add this to his protocol. It cannot and should not be ignored. You deserve this special care and it may even save your life.
Dr. Michael Rehme, DDS, CCN, practices Biological Dentistry that includes mercury free, tooth colored fillings; healthy dental materials; balancing body chemistry; and nutritional therapy. For more information about Biological Dentistry and Patient Success Stories visit http://www.ToothAndBodyConnection.com
Attend a free monthly presentation by Dr. Rehme on Biological Dentistry in the seminar room of his newly expanded office on the third Tuesday of each month @ 6:30pm. Please call to verify and reserve your space 314-997-2550.
Similar posts: stages of cancer
- Mood:Good
- Music:Kumi Koda
I have an opinion.Most people do. I try to keep my opinions humble.I feed them only vegetables and make them do yoga every morning.Despite that, they don't all stay as humble as I might like.m a Sagittarius. Once, my horoscope read, You value friendship, but you value the truth more, which is why you have so few friends.And it was a little too spot on.
Lately, my opinions have been a little restless.They said, You need to take us out more.All we ever do is sit around the house with you.And they were right.Then I thought of Livejournal, how many opinions are just floating around here that my opinions, humble as they are, could meet and hook up with.Thus was born a new post series for my LJ titled IMHO.Feel free to pronounce it I'M HO if you like, just to keep me extra humble.
Now, I don't intend to opinion about judicial law, or cat shows, bikini waxing or firearms.I'll leave that to those more knowledgeable than myself. However, I have been plugging away at a career in Speculative Fiction Writing for about four years now- long enough to form a few opinions that might actually bear some weight.
All stories must eventually go to market.That is the way of things if one hopes to pay the light bill.The trick is finding a good market, a reliable market, a market that fits, and will treat your baby right.And that can be challenging, especially for the new writer.
People will tell you different things about how to put a short story to market.Popular opinion says start at the top (meaning highest paying markets) and work your way down, until someone says I don't think that is best for several reasons.One, stories tend to get better with age, they mature, you rework them based on what editors say when they reject them.Following the popular advice above is like giving cheap wine to a wine connoisseur. Let a story age a bit, siphon through a few lower markets, then try one of the Big Dogs if you must.Second, I've come to realize that the highest paying markets aren't necessarily the best markets.Yes, getting paid pro rates is nice, great, one of the goals even, but there is much more to a market than pay rate.But what, you ask?What supersedes the almighty dollar? I'm glad you asked, because on that I have a very humble opinion.
Below is my personal list of things I look for and value in story markets, in order of priority.These are my own.They may not all apply to you, but I suggest after you read this you go prioritize your own list, and begin to choose markets based on it.Your stories will be so much happier.And so will you.
1. ACCEPTS E-SUBS:I live in New Zealand where, as far as I can tell, there is only one paying market for short speculative fiction.The internet isn't the future, it's the present.I believe the days of Self Addressed Stamped Envelopes and International Reply Coupons are long over.If a market is still using only postal submissions, IMHO it has missed the boat.
2. HAS A REASONABLE RESPONSE TIME:For me, a reasonable response time is three months maximum.A market should list its response time honestly in its guidelines.If it doesn't list it, or even if it does, it still behooves a writer to go check at the Critters Black Hole, Duotrope's Digest, or another response time source produced by writers.Keeping a story for a year without buying rights to it, IMHO, is beyond rude. The story could have been sold four times over, in that amount of time.
3. QUALITY SUBMISSION GUIDELINES:Writers get to hear a lot from editors about how we don't follow the guidelines.There seems to be an editorial belief that writers are making a concentrated effort not to do what they ask.I sympathize.m sure there are people out there coloring outside the lines.But, as a writer who painstakingly follows guidelines, I must protest.I would like writer guidelines to be easy to find on a market website.One market I recently looked at had the writer guidelines under a tab labeled Samples available online of what the market has accepted in the past are wonderful.If a market has periods closed to submissions, or themes, this should be made clear.Are the names of various editors easy to find?Is the tone of the guidelines patronizing or respectful to writers?There is a current market fad of listing pages of All the bad crap we don't want to see anymore from you writersWhen it first surfaced, I found it mildly interesting.Now, IMHO it's like listening to my thirteen-year-old describe episodes of The Simpsons I made an effort NOT to watch.EASE OF SUBMISSION:E-subs are wonderful, but can also be complicated if a market has too many technological hoops for you to jump through.Markets should make it clear if they want a sub in the body of an e-mail or, if as a file, what type.Many markets have moved to a submission form into which you paste, or download your file directly.The form takes care of the formatting, which is very nice.I love markets that have an automated response to your sub, telling you it arrived, and as this is an easy thing to set up in e-mail, I'm not sure why all markets don't do it.IMHO, modern submitting should be as simple as the click of a button.OPEN EDITORIAL PROCESS:In all honesty, I would love to put this one at the top, but it is still fairly rare.Many markets have begun to divulge their editorial process to writers, including a page that explains who reads your sub first, where it goes after that, what happens when the editor gets it.EVEN BETTER are the few and proud who provide a tracking system or number, so a writer can track their sub (much like tracking a package through the mail) as it goes from one tier to another of the submission process.Since most subs are tracked in this manner by the editorial staff anyway, why not give the writer a window into it?I know from personal experience that Andromeda Spaceways Inflight Magazine has a tracking system, and Flash Fiction Online has a wonderfully open process.IMHO, it is the ultimate perk for a writer to be informed and included in this way.
6. PAYS SOMETHING:The bottom line is- I still need to pay the light bill.I can't write in the dark.Fifteen copies of a magazine, or a free download, won't pay the light bill.A coupon for a book that will cost me $25 dollars to have shipped to New Zealand won't pay the light bill.I will look at markets that pay even a small, token amount because I can see they understand the concept of worth and may grow to pay more in the future.Perhaps it is the principle of the thing.IMHO, I think I should get paid real money for what I do.Oh, and for me, a market that can pay via PayPal is a huge bonus.The fee for cashing foreign checks in New Zealand can sometimes total more than the check itself.
So that is it, my humble list.What's on yours?What do you look for in a market and have you found any markets that you just love?Feel free to share them, and why they work for you.
Similar posts: stages of cancer
Lately, my opinions have been a little restless.They said, You need to take us out more.All we ever do is sit around the house with you.And they were right.Then I thought of Livejournal, how many opinions are just floating around here that my opinions, humble as they are, could meet and hook up with.Thus was born a new post series for my LJ titled IMHO.Feel free to pronounce it I'M HO if you like, just to keep me extra humble.
Now, I don't intend to opinion about judicial law, or cat shows, bikini waxing or firearms.I'll leave that to those more knowledgeable than myself. However, I have been plugging away at a career in Speculative Fiction Writing for about four years now- long enough to form a few opinions that might actually bear some weight.
All stories must eventually go to market.That is the way of things if one hopes to pay the light bill.The trick is finding a good market, a reliable market, a market that fits, and will treat your baby right.And that can be challenging, especially for the new writer.
People will tell you different things about how to put a short story to market.Popular opinion says start at the top (meaning highest paying markets) and work your way down, until someone says I don't think that is best for several reasons.One, stories tend to get better with age, they mature, you rework them based on what editors say when they reject them.Following the popular advice above is like giving cheap wine to a wine connoisseur. Let a story age a bit, siphon through a few lower markets, then try one of the Big Dogs if you must.Second, I've come to realize that the highest paying markets aren't necessarily the best markets.Yes, getting paid pro rates is nice, great, one of the goals even, but there is much more to a market than pay rate.But what, you ask?What supersedes the almighty dollar? I'm glad you asked, because on that I have a very humble opinion.
Below is my personal list of things I look for and value in story markets, in order of priority.These are my own.They may not all apply to you, but I suggest after you read this you go prioritize your own list, and begin to choose markets based on it.Your stories will be so much happier.And so will you.
1. ACCEPTS E-SUBS:I live in New Zealand where, as far as I can tell, there is only one paying market for short speculative fiction.The internet isn't the future, it's the present.I believe the days of Self Addressed Stamped Envelopes and International Reply Coupons are long over.If a market is still using only postal submissions, IMHO it has missed the boat.
2. HAS A REASONABLE RESPONSE TIME:For me, a reasonable response time is three months maximum.A market should list its response time honestly in its guidelines.If it doesn't list it, or even if it does, it still behooves a writer to go check at the Critters Black Hole, Duotrope's Digest, or another response time source produced by writers.Keeping a story for a year without buying rights to it, IMHO, is beyond rude. The story could have been sold four times over, in that amount of time.
3. QUALITY SUBMISSION GUIDELINES:Writers get to hear a lot from editors about how we don't follow the guidelines.There seems to be an editorial belief that writers are making a concentrated effort not to do what they ask.I sympathize.m sure there are people out there coloring outside the lines.But, as a writer who painstakingly follows guidelines, I must protest.I would like writer guidelines to be easy to find on a market website.One market I recently looked at had the writer guidelines under a tab labeled Samples available online of what the market has accepted in the past are wonderful.If a market has periods closed to submissions, or themes, this should be made clear.Are the names of various editors easy to find?Is the tone of the guidelines patronizing or respectful to writers?There is a current market fad of listing pages of All the bad crap we don't want to see anymore from you writersWhen it first surfaced, I found it mildly interesting.Now, IMHO it's like listening to my thirteen-year-old describe episodes of The Simpsons I made an effort NOT to watch.EASE OF SUBMISSION:E-subs are wonderful, but can also be complicated if a market has too many technological hoops for you to jump through.Markets should make it clear if they want a sub in the body of an e-mail or, if as a file, what type.Many markets have moved to a submission form into which you paste, or download your file directly.The form takes care of the formatting, which is very nice.I love markets that have an automated response to your sub, telling you it arrived, and as this is an easy thing to set up in e-mail, I'm not sure why all markets don't do it.IMHO, modern submitting should be as simple as the click of a button.OPEN EDITORIAL PROCESS:In all honesty, I would love to put this one at the top, but it is still fairly rare.Many markets have begun to divulge their editorial process to writers, including a page that explains who reads your sub first, where it goes after that, what happens when the editor gets it.EVEN BETTER are the few and proud who provide a tracking system or number, so a writer can track their sub (much like tracking a package through the mail) as it goes from one tier to another of the submission process.Since most subs are tracked in this manner by the editorial staff anyway, why not give the writer a window into it?I know from personal experience that Andromeda Spaceways Inflight Magazine has a tracking system, and Flash Fiction Online has a wonderfully open process.IMHO, it is the ultimate perk for a writer to be informed and included in this way.
6. PAYS SOMETHING:The bottom line is- I still need to pay the light bill.I can't write in the dark.Fifteen copies of a magazine, or a free download, won't pay the light bill.A coupon for a book that will cost me $25 dollars to have shipped to New Zealand won't pay the light bill.I will look at markets that pay even a small, token amount because I can see they understand the concept of worth and may grow to pay more in the future.Perhaps it is the principle of the thing.IMHO, I think I should get paid real money for what I do.Oh, and for me, a market that can pay via PayPal is a huge bonus.The fee for cashing foreign checks in New Zealand can sometimes total more than the check itself.
So that is it, my humble list.What's on yours?What do you look for in a market and have you found any markets that you just love?Feel free to share them, and why they work for you.
Similar posts: stages of cancer
- Mood:More emotions
- Music:Heartbreak Hotel
